Immune Responses to Salmonella

Salmonella infection is one of the most important zoonotic threats to humans affecting animal health and thus our food supply. Our group is currently working on two projects addressing Salmonellosis.

  1. The influence of microbiota on the host's immune response to Salmonella: Microbiota of the human intestine provides an important protective function against enteric pathogens. The project analyzes the interaction of normal or reduced microflora in an enteric infection model with Salmonella and the influence of the microbiota on the host immune response to Salmonella.
  2. Immune functions mediating immunity or susceptibility to chronic Salmonellosis in dairy cattle: We seek to identify parameters of the immune response that are associated with immunity to chronic Salmonella infection in cattle. The goal is to include these immune parameters in the development of new vaccine strategies to Salmonellosis to improve animal health and food safety.