Our previous findings showed that foals do not produce IgE antibodies for almost the first year of life. However, clearly detectable amounts of IgE are transferred from mares to offspring with the colostrum after birth. In this project, we test how maternal IgE influences the susceptibility to allergy in neonates.
References
Wagner B, Burton A, Ainsworth D
Vet Res. 2010 Jul-Aug;41(4):47. doi: 10.1051/vetres/2010019. Epub 2010 Apr 9.
Induction of interleukin-4 production in neonatal IgE+ cells after crosslinking of maternal IgE
Wagner B, Stokol T, Ainsworth DM
Dev Comp Immunol. 2010 Apr;34(4):436-44. doi: 10.1016/j.dci.2009.12.002. Epub 2009 Dec 16.
Serum interleukin-6 (IL-6) and IL-10 concentrations in normal and septic neonatal foals
Burton AB, Wagner B, Erb HN, Ainsworth DM
Vet Immunol Immunopathol. 2009 Dec 15;132(2-4):122-8. doi: 10.1016/j.vetimm.2009.05.006. Epub 2009 May 18.
Wagner B, Flaminio JB, Hillegas J, Leibold W, Erb HN, Antczak DF
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